Computational Methods in Systems Biology

This book contains revised selected papers from the International Conference on Computational Methods in Systems Biology (CMSB 2004), which was held in Paris, France in May 2004. It features cutting-edge research in the field of systems biology, exploring various computational methods for analyzing and modelling complex biological systems. The book covers a broad range of topics, including: * **Gene Regulatory Networks:** Understanding the intricate interactions between genes and their regulatory elements, using computational methods to model and analyze gene expression data. * **Metabolic Networks:** Modelling metabolic pathways, analyzing flux distribution, and predicting the impact of genetic or environmental changes on metabolism. * **Signalling Pathways:** Computational analysis of signal transduction pathways, identifying key components, and modelling dynamic responses. * **Systems Biology of Disease:** Application of computational approaches to study disease mechanisms, identify drug targets, and develop personalized medicine strategies. * **Computational tools and software:** The book also explores the latest developments in computational tools and software for systems biology, including algorithms, databases, and analysis platforms. This book is a valuable resource for researchers, students, and professionals in the fields of bioinformatics, computational biology, and systems biology. It offers insightful perspectives, innovative methods, and practical applications for advancing the field of systems biology.